lymphoma of the skin

Everyone has their own way of dealing with illness and the different emotions they experience. About Cancer generously supported by Dangoor Education since 2010. Primary cutaneous lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up, Annals of oncology 2013 volume 24 (Supplement 6) pages 149– 154, European Organisation for Research and Treatment of Cancer consensus recommendations for the treatment of mycosis fungoides/Se´zary syndrome e Update 2017, European Journal of Cancer 2017 Volume 77, pages 57-74, Cancer: Principles and practice of oncology (11th edition) Cutaneous T-cell lymphoma is a disease that affects the immune system. This information has been written, revised and edited by Macmillan Cancer Support’s Cancer Information Development team. Round patches of skin that may be raised or scaly and might be itchy 2. To have the treatment your nurse connects you to a special machine by a drip. They can arrange for you to see a specialist at the hospital for tests and advice. This is called an allogeneic stem cell or bone marrow transplant. Knowing the type and grade of the lymphoma helps doctors decide on the best treatment and how soon it should start. Before a transplant, you have high dose treatment to destroy the stem cells in the bone marrow. The key is to notice when something's off and check in with your doctor. They want to find out how people feel about their treatment and care. They start to divide constantly but don't develop fully. When lymphoma affects the skin, it may cause a rash that appears as one or … The nurse or doctor treats the separated white blood cells with a light sensitising drug (psoralen). Making small changes such as eating well and keeping active can improve your health and wellbeing and help your body recover. Waiting for tests results can be a difficult time, we have more information that can help. There have been some good responses to a drug called alemtuzumab (Campath) in some patients with CTCL. We used many references and there are too many to list here. Talking about how you feel can help. CBCL is a more unusual type. The most common are called mycosis fungoides and Sézary syndrome. For information about cutaneous B cell lymphoma, visit the Lymphoma Action website. CTCL generally comes back and so you may need PUVA treatment again. Further testing. A specialist doctor (pathologist) examines it under a microscope, looking for cancerous T cells. In the early stages, CTCL can look like other skin conditions, such as eczema or psoriasis. It can appear as a single patch or in several areas of the body. In this type of lymphoma the normal structure of the lymph node is disrupted and the lymphoma cells have spread widely (diffusely) throughout the lymph node. Many people have this treatment for a year or more. You have it 4 to 5 days a week for between 2 and 5 weeks. This treatment is only available in some specialist centres. You need to wear gloves when putting the cream on because the chemotherapy drug harms normal skin. They will also talk to you about the things you should consider when making treatment decisions. There may be signs of abnormal lymphocytes in the lymph nodes. Other symptoms of lymphoma may depend of the specific type you have. Short term side effects may include skin redness, dry and itchy skin, and a rash. The main concern is to treat your current lymphoma. Doctors call this watch and wait. Available from: www.annalsofoncology.org/article/S0923-7534(19)31554-6/pdf. Treatment directly to the skin is also called topical treatment. The stage of CTCL describes how much of the skin is affected and if it has spread anywhere else. A skin biopsy is always required for a diagnosis of lymphoma. When it's in your chest, it can hurt and cause trouble breathing. Your cancer doctor or specialist nurse will explain the different treatments and their side effects. This may lead to: Other symptoms will depend on where in your body the Hodgkin lymphoma is. There may be one or more tumours on the skin that are greater than 1cm. To have the treatment, you take psoralen tablets. The symptoms can stay the same for many years and many people never progress beyond the first stage. Enlarged lymph nodes 5. Like other cancers, it is not infectious and can not be passed on to other people. Or you may have it for clearing up patches that remain after PUVA treatment. Radiotherapy uses high energy x-rays to kill cancer cells. TLO-1 treatment does not go as deep into the skin as PUVA treatment. VT De Vita, TS Lawrence and SA Rosenberg It develops when cells called T-cells (also called T-lymphocytes) become abnormal. Signs and symptoms of cutaneous T-cell lymphoma include: 1. There may be any of the skin symptoms described in the previous stages. Non melanoma skin cancers are treatable. 24 (Supplement 6), vi149–vi154. Symptoms of cutaneous T-cell lymphoma (CTCL), Causes of cutaneous T-cell lymphoma (CTCL), Diagnosis of cutaneous T-cell lymphoma (CTCL), Stages of cutaneous T-cell lymphoma (CTCL), Treatment for cutaneous T-cell lymphoma (CTCL), After cutaneous T-cell lymphoma (CTCL) treatment, What's going on near you? Your nurse can teach you how to give the injection yourself. 9.4.4 Cutaneous T-Cell Lymphoma CTCLs are the most frequent primary lymphomas of the skin. The lymphatic system is a network of thin tubes and lymph nodes that run throughout the body. There are also cancerous T cells (called Sezary cells) in the blood. There is a small increased risk of non melanoma skin cancer in the treatment area. Oftenly lymphoma appears in parts of the skin which are not exposed to the sun. It causes flat red patches on the skin that look like eczema and can be itchy. Having this procedure does not hurt, but some people may feel a bit weak or dizzy during or after it. It has been reviewed by expert medical and health professionals and people living with cancer. It might help to let friends and family know if you are finding it difficult to cope. It works by stimulating your immune system to control the lymphoma. But it uses UVB light rather than UVA. So they can't fight infection as normal white blood cells do. This drug helps the body’s immune system target cancer cells. Lymph nodes are part of the body’s lymphatic system. Your blood, minus the white blood cells, then goes back into your vein. Types of non-Hodgkin lymphoma. Drugs include: You might have one chemotherapy drug or a combination of drugs. Psoralen ultraviolet light treatment (PUVA) is very helpful for plaques and larger areas of CTCL. The side effects of TLO-1 treatment are similar to PUVA, but there is a lower risk of developing non melanoma skin cancer with narrow band UVB treatment. Blastic plasmacytoid dendritic cell neoplasm presents with bruise-like plaques, nodules and tumours. Clinically, lymphoma from the cells of the follicular centers is manifested by single, often multiple nodes or plaques on the scalp, trunk. We have more information about risk factors for non-Hodgkin lymphoma. You can have it as tablets or into a vein (intravenously). This will begin to disappear once the treatment is over. Mycosis fungoides (MF) is the most prevalent clinical form (70%) followed by Sézary syndrome (SzS), which is a more aggressive leukemic T-cell disorder associated with generalized erythroderma and lymphadenopathy. But you can have treatment a second time when the lymphoma comes back. You take bexarotene as a capsule. Most of these conditions are generally termed ‘primary cutaneous lymphomas’. In the UK, doctors most commonly use a chemotherapy drug called carmustine (BCNU). Rashes are most commonly seen in lymphomas of the skin. There are also charities, such as the Lymphoma Association who can provide support and information. A team of specialists will meet to discuss the best possible treatment for you. If you have a lymphoma that has spread to the skin, our information on the particular type of lymphoma you have will be more relevant for you. They filter out disease and germs (bacteria and viruses) as fluid passes through them. Sezary syndrome is a faster growing (high grade) type of CTCL. Primary Cutaneous Marginal Zone B-Cell Lymphoma : This slow-growing lymphoma is the second most common form of CBCL and appears as pink or red lesions, nodules, and/ or tumors, most commonly … They may appear as reddish or purple scaly areas. Isle of Man company number 4694F. Lymphoma of the Skin Lymphoma of the Skin SAXE, NORMA; KAHN, LEONARD B.; KING, HELEN 1977-06-01 00:00:00 A clinico‐pathologic study of lymphomas of the skin included 14 cases of mycosis fungoides, 14 of primary lymphoma and 22 of secondary lymphoma. It also wants to find out about the needs of their carers. We have more information about treatment for cutaneous T-cell lymphoma. The sample is then examined under a microscope for abnormal cells. After this process, your nurse gives back the treated white blood cells into your vein. There are 4 main stages for mycosis fungoides. Then your body makes the blood cells you need again. Stage 1A – less than 10% of the skin is affected. You will have regular blood tests to check these. Lymphoma can sometimes cause an itchy rash. It is helpful for early stage CTCL. Please contact [email protected] with details of the particular issue you are interested in if you need additional references for this information. The causes of CTCL are not known. It may help for months rather than years. Annals of Oncology. The main subtypes are: 1. This is usually in the neck, armpit or groin. About 2 hours later the doctor shines an ultraviolet light onto your skin. Even if you already have a healthy lifestyle, you may choose to make some positive lifestyle changes after treatment. © Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). This light activates the drug so that it is able to destroy the lymphoma cells. Some people decide to have counselling. You may need to take tablets to keep these levels within normal ranges. The most common types of CTCL are mycosis fungoides (pronounced my-coh-sis fun-goyd-eez) and Sezary syndrome. Knowing the stage helps your doctors plan the best treatment for you. It can be difficult coping with a rare type of cancer as you may not meet many people in a similar situation. Diagnosing skin lymphoma can be difficult. Doctors are testing newer treatments for cutaneous T cell lymphomas. The medical term used for skin is ‘cutaneous’. Lymphoma is a type of cancer that starts in immune cells called lymphocytes. This article elucidates the symptoms, causes and treatment of the … Doctors use it to treat people with advanced CTCL, especially Sezary syndrome. You usually have it for more advanced CTCL that has come back after other treatments. The lymph nodes may or may not be affected. Mycosis fungoides is a very slow growing (low grade) type of CTCL. Lymph nodes are bean shaped glands. You usually have treatment 2 times a week until there is no sign of lymphoma. Doctors usually only suggest this type of treatment to people who are young and fit and are most likely to be able to cope with the side effects. This is called topical chemotherapy. You have regular check ups with your specialist. There are many different targets on cancer cells and different drugs that target them. Lymphoma arises mainly from the uncontrolled proliferation of T-cells and can become cancerous.. T-cell lymphoma is categorized under Non-Hodgkin Lymphoma (NHL) and represents less than 15% of all Non-Hodgkin's diseases in the category. Your doctor will talk to you about taking care in the sun, and will watch you for signs of skin cancer. The main concern is to treat the lymphoma. Retinoids are a group of drugs related to vitamin A. This specialist is often a dermatologist (a doctor who treats skin problems) or a lymphoma doctor. Lymphoma can make your skin itchy or give you red bumps. You usually have the treatment again the following day. Psoralen (P) is a drug that makes your skin very sensitive to ultraviolet light (UVA) for about 24 hours. Rare lymphomas that start in the skin are called skin lymphomas (or cutaneous lymphomas). The stage shows how much of the skin is affected by lymphoma, and whether it has spread to the lymph nodes or other body organs. Most are slow growing (low grade) but some can be fast growing (high grade). Doctors usually use treatments to treat the skin directly when CTCL is at an early stage. Some types of skin lymphomas occur as a rash over some or most of the body. The information on this page is based on literature searches and specialist checking. In the early stages, the skin patches can look like other common conditions such as eczema or psoriasis. You usually start by seeing your GP. Emollients help to prevent loss of water from your skin by creating a protective layer. A biopsy is a procedure to remove abnormal tissue to look at it under the microscope by a pathologist (a specialist doctor). There may be any of the skin symptoms described in the previous stages. We’ve created a new account area offering personalised cancer information and support. Your nurse will give you paracetamol before you have the interferon injection to help with some of these side effects. Your donations make it happen. For most people, Mycosis fungoides will develop slowly or stay under control for many years. But your nurse and doctor will monitor you closely for this. An anonymous network of people affected by cancer which is free to join. Bexarotene is a retinoid. When treatment finishes, your doctor will monitor you regularly in clinic. These help to relieve itching and can clear up patches or plaques of CTCL for long periods of time. A company limited by guarantee, registered in England and Wales company number 2400969. Cutaneous T-cell lymphoma (CTCL) is a type of skin lymphoma. This type of lymphoma is regarded as aggressive and tends to spread over weeks or months from the lymph node to other areas of the body including the skin, gut, central nervous system and bone. They are part of our immune system. Skin lymphoma (or ‘cutaneous’ lymphoma) is a rare condition that can be hard to diagnose. A few people do not have any symptoms until they notice raised lumps (tumours) on the skin. They can include: In the long term, there is an increased risk of developing other types of skin cancer. There are different types of CTCL. Doctors have been looking at whether having lenalidomide after chemotherapy can prevent or delay the CTCL coming back. Sometimes a side effect may continue or develop months or years after treatment. It develops when cells called T-cells (also called T-lymphocytes) become abnormal. If a biopsy confirms a diagnosis of non-Hodgkin lymphoma, further testing will be required to check how far the lymphoma has spread. There are more than 30 types of non-Hodgkin lymphoma. You usually have it for CTCL that has not responded to other treatment, or has come back. The skin in the treatment area may become slightly red and sore. You usually have between 2 and 5 treatments. Ask your consultant or specialist nurse for advice about how to look after your skin and ways to make it more comfortable. The goal of the session is to succinctly review recent developments in lymphoma classificat … When you have lymphoma, some of your lymphocytes don't work properly. Treatments include steroid creams or gels, and chemotherapy cream. Stage 1B – 10% or more of the skin is affected. For example, you will have eye shields to protect your eyes. Over time, the elements may ulcerate. CD30 is a protein that is sometimes found on cutaneous T cell lymphoma (CTCL). Stem cells are very early blood cells in the bone marrow that develop into red blood cells, white blood cells and platelets. Lymphoma of the skin is a type of non-Hodgkin lymphoma that can either affect the T-cells or B-cells, which are the two types of lymphocytes. Learn more about the symptoms, causes, diagnosis, and treatment of lymphoma in this in-depth article from WebMD. Interferon is a type of immunotherapy. A lymphoma that starts somewhere else in the body and then spreads to the skin is not a skin lymphoma. Runs a service providing individual teaching sessions on how to use camouflage make-up. Targeted cancer drugs work by ‘targeting’ those differences that help a cancer cell to survive and grow. It is closely related to mycosis fungoides but most or all of the skin is covered in a red itchy rash. A monoclonal antibody is a drug that targets specific proteins on cancer cells. Hodgkins lymphoma and the more prevalent Non-Hodgkins lymphoma, both of which can cause lymphoma rash in addition to similar symptoms. These are high dose treatments used for some types of cancer. You may have interferon on its own. So you usually only have it to treat patches and very thin plaques of disease. So it is not unusual to have more than one biopsy over a number of weeks or months. The drug Brentuximab is a monoclonal antibody that targets the CD30 protein. Chemotherapy uses anti cancer (cytoxic) drugs to destroy cancer cells. Hair loss 6. Lymphoma of the Skin Lymphoma is a cancer that starts in cells that are part of the body's immune system. It has been approved by Senior Medical Editor, Professor Rajnish Gupta, Macmillan Consultant Medical Oncologist. Wolters Kluwer, 2019, Phase II multicentre trial of oral quisinostat, a histone deacetylase inhibitor, in patients with previously treated stage IB-IVA mycosis fungoides/Sézary syndrome, British Journal of Haematology 2016 Volume 175(1) pages 80-88. TSEBT works well. You have interferon as an injection under the skin. The biopsy can be done under local or general anaesthetic depending on what part of the body is being biopsied. The patches can appear anywhere on the body but are more often found on the chest, abdomen, back and buttocks. Some lymph nodes are enlarged. Several parts of the body can be affected. Mycosis fungoides is usually a very slow-growing type of lymphoma that often only affects the skin. There are two types of lymphoma, i.e. Lumps that form on the skin and may break open 4. It can also be hard to live with the symptoms, such as itchy, sore and dry skin. It usually affects people aged 40 to 60 and is more common in men than women. VAT no: 668265007. CTCL may cause changes to the skin, including: Some people with CTCL have lumps where a lymph node is swollen. Your doctor will weigh up the risks and benefits of treatment and talk you through them. A rash-like skin redness over the entire body that is intensely itchy It is considered a cancer and it is a non-Hodgkin’s type of lymphoma. Mycosis fungoides has clinical and histopathologic features which allow for separation from the other groups. These treatments may be given as tablets, or as an injection into a vein or under the skin. Lymphoma is a cancer of the lymphatic system, which is part of the body's germ-fighting network.The lymphatic system includes the lymph nodes (lymph glands), spleen, thymus gland and bone marrow. This stage is divided into two groups: As for most cancers, treatments depend on the stage of the disease when it is diagnosed. These include creams, light therapy and radiotherapy. They will take a small sample (a skin biopsy) from an area of affected skin. Lymphoma is a term that is used to describe a variety of cancer. Registered office: 89 Albert Embankment, London SE1 7UQ. And early trials have looked at another type of monoclonal antibody called zanolimumab, with promising results. Answer four quick questions to get specially selected content for you. Primary cutaneous lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. People with Sezary syndrome often have a weakened immune system. You have it in a specialist centre. It has a national network of people with lymphoma and local groups. There are different types of CTCL. Our cancer information has been awarded the PIF TICK. Hodgkin's lymphoma (formerly called Hodgkin's disease) 2. For example, if the abdomen (tummy) is affected, you may have abdominal pain or indigestion. Doctors have looked at HDAC inhibitors for CTCL including: Researchers know that some people are treated for T cell lymphoma of the skin for many years. Afterwards your skin and eyes may be more sensitive to sunlight for about 24 hours. We help people get through cancer. Or you have it for a maximum of 30 treatments. Radiotherapy to the skin does not have very many side effects. Doctors generally prescribe topical steroids for short periods as they can cause side effects such as skin thinning in the affected area. Changing Faces provides free help, support, and information for people with a facial disfigurement. Your doctor or nurse will give you advice about protecting your skin and eyes from ultraviolet light and for how long. Share experiences, ask questions and talk to people who understand. You can read more about further tests you may have in our information about non-Hodgkin lymphoma. Rarely, the disease becomes more advanced and the skin appears red, swollen and sore all over. The Macmillan Cancer Support website has detailed information on the different types of non-Hodgkin lymphoma. We have more information about long-term and late effects of treatment for lymphoma. Chemotherapy often works well for CTCL, but unfortunately the response does not usually last very long. It is … These appointments are a good opportunity for you to talk to your doctor or nurse about any concerns you have. You usually have an injection to numb the area first. T-cell skin lymphomas are skin lymphomas that develop from T cells. If you would like to talk, you can: The organisations below also offer information and support: Blood Cancer UK is a blood cancer research charity that provides information and support on any type of blood cancer. There are 2 types of lymphocytes or white blood cells: In cutaneous lymphoma the T cells or B cells grow out of control within the skin. In a few cases the cancerous cells can spread to the lymph nodes or organs such as the liver. ECP is a type of PUVA treatment that treats the blood. Call freephone 9 to 5 Monday to Friday or email us, Find out more about stem cell and bone marrow transplants, cutaneous T cell lymphoma (CTCL) starts in the T cells of the skin, cutaneous B cell lymphoma (CBCL) starts in the B cells of the skin, stage 1A means that the lymphoma affects less than 10% of the skin, stage 1B means that the patches or plaques have become more widespread, affecting more than 10% of the skin, stage 2A means there are patches or plaques on the skin and the lymph nodes are swollen, but there are no cancerous T cells there, stage 2B means there are one or more lumps (tumours) in the skin, stage 3A means that most of the skin (more than 80%) appears red and sore (erythrodermic mycosis fungoides), stage 3B is the same as 3A, but there are some cancerous T cells (Sezary cells) in the blood, stage 4A1 means there are high numbers of cancerous T cells (Sezary cells) in the blood (Sezary syndrome), stage 4A2 means there are cancerous T cells in the lymph nodes, stage 4B means the cancer has spread to other organs of the body, such as the liver or spleen, psoralen ultraviolet light treatment (PUVA). After the high dose treatment you have stem cells or bone marrow into a vein through a drip. You may find it helpful to talk things over with family and friends or your doctor or nurse. Lymphoma can affect all those areas as well as other organs throughout the body.Many types of lymphoma exist. In a small number of people, raised lumps (tumours) can appear. You can get side effects up to 6 months after the treatment. Many skin lymphomas are slow growing, so you might not need treatment straight away. Find the nearest Macmillan information and support centre, Coronavirus (COVID-19) guidance for people with cancer, Coronavirus guidance if you have recovered from cancer, Shielding – Taking care of yourself at home, Self-isolation advice during the coronavirus outbreak, The latest updates to Macmillan's services, Coronavirus vaccine for people living with cancer, Coronavirus guidance for people worried they have cancer, Coronavirus information for healthcare professionals, Primary mediastinal large B-cell lymphoma (PMBCL), MALT lymphoma (extranodal marginal zone lymphoma), Angioimmunoblastic T-cell lymphoma (AITL), long-term and late effects of treatment for lymphoma, www.annalsofoncology.org/article/S0923-7534(19)31554-6/pdf. A few people with advanced CTCL have treatment with high dose chemotherapy and a stem cell or bone marrow transplant. Mycosis fungoides often starts as an irregular shaped area of dry or scaly skin. More than 80% of the skin is red (erythroderma). Histone deacetylase (HDAC) inhibitors block enzymes (histone deacetylases) in the body which cells need to grow and divide. The different stages of CTCL are: There are red patches or raised red patches (plaques) on the skin. You have it to control symptoms and make you more comfortable. The rest of the information on this page is about cutaneous T cell lymphoma. You could also ask if there are any support groups at your hospital or within your local area. The treatment itself takes between 3 and 4 hours, and you have the 2 day cycle every 2 to 4 weeks. There are 2 main types of skin lymphoma: CTCL is the most common type of skin lymphoma. CTCL mainly affects the skin, but can also involve lymph nodes, blood, and … What is cutaneous T-cell lymphoma (CTCL)? Search our clinical trials database for all cancer trials and studies recruiting in the UK, Questions about cancer? A study is looking at the care and support needs of people with T cell lymphoma of the skin. Your blood goes through the machine, which separates off some of your white blood cells. They then expose them to ultraviolet light (UVA). PCDLBCL-other includes large B-cell lymphoma, which presents with skin lesions on the head, the trunk or the extremities. Your doctor may suggest using a moisturising cream every day and adding an emollient to the bath water to help with skin dryness and relieve mild itching. CTCL usually develops very slowly. Macmillan is also here to support you. If you have radiotherapy to a part of the body that has hair, you will have some temporary hair loss. Cutaneous (skin) lymphomas can develop from B-cell lymphocytes or T-cell lymphocytes. This is similar to PUVA treatment. Mutations occur with the T-cells, which typically move to the outer layers of the skin. Cutaneous T-cell lymphomas account for around 75% of all cutaneous lymphomas. Many types of CTCL start as flat red patches on the skin, which can sometimes be itchy. For some very slow growing types of CTCL, treatment might not need to start straight away. … One type of T-cell lymphoma is cutaneous T-cell lymphoma (CTCL). We have more information about signs and symptoms of lymphoma. For CTCL, you usually have stem cells or bone marrow from another person. You might have this treatment if you have already been treated previously with another drug. They are looking at the following treatments: These are a type of targeted therapy. Researchers are looking at treatment for CTCL and how people with CTCL are cared for. Lymphoma from the cells of the follicular center (blue follicular lymphoma) is the primary lymphoma of the skin. Also operating in Northern Ireland. Lymphoma Action gives emotional support, advice and information on all aspects of Hodgkin lymphoma and non-Hodgkin lymphoma. 2013. For some very slow growing types of skin lymphoma, treatment may not need to start straight away. In a small number of people, Mycosis fungoides may spread to other parts of the body over time. So there is an increased risk of infection. It is a rare type of non-Hodgkin lymphoma. Lymphoma is cancer that stems from the lymphocytes, which are the white blood cells that … Tissue fluid called lymph circulates around the body in these vessels and flows through the lymph nodes. This chapter describes the various ways in which the non-Hodgkin's lymphomas can involve the skin, how these diseases should be assessed, standard treatments available in 2002, and new directions in research. Stage 1 only affects the skin (in patches or plaques). The lymph contains a high number of white blood cells (lymphocytes) which fight infection. Lymphoma is cancer of the lymphatic system. The Macmillan Support Line offers confidential support to people living with cancer and their loved ones. It is a rare type of non-Hodgkin lymphoma. cutaneous T cell lymphoma (CTCL) starts in the T cells of the skin Abnormal lymphocytes have spread to the lymph nodes or the blood. T-cells are white blood cells that fight infection. This is called a multidisciplinary team (MDT). If you’re diagnosed with cancer, your worries are our worries and we will move mountains to help you live life as fully as you can. Patches of skin that appear lighter in color than surrounding skin 3. You have this 3 times a week. Sometimes larger lesions can form. This is called erythrodermic mycosis fungoides. However it does not keep the CTCL under control forever. Skin Lymphoma: The Illustrated Guide has been designed to alleviate some of these difficulties, providing all those working in the dermatological field with a complete and easily consulted text on this potentially fatal cancer. This stage is sometimes divided into: Skin symptoms are the same as in stage 1. cutaneous T-cell lymphoma (CTCL) and cutaneous B-cell lymphoma (CBCL These abnormal areas of skin might form scaly raised patches, called plaques. So you need to protect yourself from the sun and also need to wear sunglasses. Let’s Face It provides support, information, social activities and advice on camouflage make-up for people with a visible facial difference. Other people might notice your skin and it could make you conscious of your condition.

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